Hi. I’ve added to an old post but I thought I’d start a new one in case that one doesn’t get seen. I started HRT 4 years ago, first on gel for a few months, then Lenzetto. Neither caused a reaction but specialist thought patch would suit me better. I changed to Oestrodot, I was on it for a few months with no skin reaction but had acid reflux get worse, and I suspect I’m intolerant to soya so I was changed on to Evorel. I was fine on this for 5 weeks before developing an angry, red itchy rash underneath. Specialist moved me back on to Lenzetto which also caused a rash, she put me back on Oestrodot, the same thing happened, an angry itchy rash. All of these things have left marks which are taking weeks to heal. This morning I tried the gel again and lo and behold, I now have a raised red rash on my inner thighs. I don’t understand why I’m suddenly reacting to everything I was previously fine on. I can’t take oral oestrogen because I’m on thyroid meds. I have low bone density which is why I’m desperate to stay on HRT, aside from anxiety, night sweats etc of course. I saw people had posted previously about this but no final solutions are mentioned. Can anyone help, I’m feeling pretty desperate right now. Thank you.