Two thoughts...
Vaginal dryness (if it's the only symptom left) is usually best treated with local estrogen like Vagifem or Ovestin, rather than increasing systemic estrogen. And itchiness can actually be due to too much estrogen or to histamine involvement, caused by raising estrogen. Which is all to say - you might not have needed this dose increase and might have been better staying at 50 and adding in local vaginal estrogen.
My other thought is you might need testosterone as well. This can have a big impact on mood and sleep. If you find it hard to get via your GP, you can make a reduced cost appointment for 'testosterone only' at a clinic like the Newson Clinic for eg....