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[Blue Kingfisher]

Hi everyone,

I haven’t been on here for a while as I’ve been trying a conti regime which I’ve now been on for 3 months: 100mg Utro vaginally every night with 4 pumps oestrogel (3am, 1pm). I kept going with it, although I’ve felt blooming dreadful, just in case it started to get better. It didn’t get better for me, it got worse. I’ve felt exhausted, headachey, spaced out, depressed, brain fog and a shadow of my former self.

I’ve obviously decided that’s quite enough, point proven and next trial please. I didn’t take any Utro last night for the first time, feel very slightly better but not expecting to feel much better for a while obviously as I’ve no idea how long it will take to come out of my system.

I can’t decide whether to try Utro 100mg every other night or give my body a break from progesterone and try a long sequi cycle. Im terrified of sequi as the withdrawal can be devasting for me so I’m not sure which way to go. I really don’t want to take Utro again tonight but I’m worried I will be so bad with the withdrawal that I won’t be able to function next week (& it’s a busy one with deadlines).

Does anyone know btw what a long cycle on 100 Utro might be? Is it 4 weeks oestrogen only followed by 2 weeks of Utro? I think to go back to sequi, it would either have to be a long cycle (to make the withdrawal trauma worth it) or just 7 days off a Utro a month so the withdrawal doesn’t last too long (mine can go on for some time).

I know no one can really help me but myself in this situation but any advise or thoughts very much appreciated x

[Perinowpost]

Hi Blue we’ve spoken before, as we both suffer progesterone Intolerance. Well done for sticking with it 3 months, don’t think I could have done that. I once took utrogestan for 12 days and had a near death experience when I came off my bike on a fast road - so never again!

To answer your question I think long cycle is more like 6 weeks with 12 days utro. Maybe try alternative days to start with in the short term to avoid the (horrible) withdrawal.

In the meantime I’m on the same journey as you and am about to trial Lutigest as a last attempt after trying everything else available.

Wishing you well, let us know how you get on x

[Blue Kingfisher]

Thanks Perinowpost, I’m very tempted to not use an Utro tonight as there was a threat of me having a sense of humour this evening (that hasn’t happened in a long while), I’m also not in bed yet at 9:30ish so that’s also a positive change…

I think whatever I’ll do I’ll regret it to be honest so I’ll probably try going to bed without Utro & see how I go. Thanks for the advice on the long cycle…so do you think the 12 days of Utro are within the six week period i.e. oestrogen only for 30 days and then with Utro for 12 days? I presume also it’s 200mg Utro each night as opposed to 100mg? I think I could manage the 12 days on 200mg at a push but it would be the withdrawal that I’m not sure about.

Anyway, your close encounter to a horrible accident sounds very scary & I don’t blame you for not wanting to retry Utro! I’ve no idea what Lutigest is? Is it synthetic? I must admit, I’ve only tried Utro and a coil so should probably consider other options if my next couple of options draw a blank.

[Perinowpost]

I think it’s 200mg if it’s orally and 100mg if vaginally but don’t quote me, someone else might be along to confirm.

No Lutigest is body identical like utrogestan. I had to get it on private prescription (£35) to try it, but that’s 4 months supply. It’s worth a try. Like you I struggle with withdrawals terribly and think my next stop may be hysterectomy, although I don’t really want one.

Btw I was offered utro 100mg vaginally alternate days as a solution to prog intolerance by my specialist but couldn’t even tolerate that. But just to say it is a recognised alternative x

[Blue Kingfisher]

I hope you get on better with Lutigest, I’d be interested to know. When are you starting it & are you going to try sequi or conti to start? When you suffer from progesterone withdrawal, how long does this typically last for you?

I’m anticipating feeling really bad for a week or so initially once I start bleeding, but then, when the progesterone has really come down (at around day 8 after bleeding started) that I start to feel worse again. The second phase of crapness, usually worst than the first, I think could be driven by too high Oestrogel. It will be interesting to see how I go this time round as I haven’t been through withdrawal now for some time.

I didn’t take Utro last night so that’s two nights without it in a row so I’m starting to feel better but no bleed yet. I think the horrible progesterone withdrawal is yet to start for me. I’d imagine it will kick in tomorrow or the day after (since I’ve been on conti for 3 months). I might be reaching for Utro again if it becomes too bad as I can’t take time off at the moment.

I’ve also considered hysterectomy but like you, very unkeen.

[Perinowpost]

Thanks, I usually take prog the beginning of the month, but I’m going to delay this time for a few days as it’s my husband’s birthday and we’re going away. Even so not long to go. I’m going to take it sequi i.e., vaginally x 7 days to start with. Only because I’ve never managed to tolerate any conti regime. I’ll let you know how I get on.

Withdrawal usually lasts for about a week with me, with days 3 & 4 after stopping taking it the worst and then slowly tapering back to my normal self. I feel mentally ill for those couple of days and it’s quite frightening. I’m don’t have any mental health issues any other time so it’s quite a lot to put myself through and I dread it every time. My specialist said my receptors are particularly sensitive. I’ve researched it and approximately 1 in 20 suffer from progesterone intolerance, but maybe not all to the same extent as us.

Anyway keep us posted how you’re feeling, always here xx

[discogirl]

sorry to cut in but wanted to ask you ladies how does utro make you feel.

im trying to sort my sleep out and im so scared of utro disturbing my sleep even more (if thats possible) i take it vaginally too but in the mornings.

it doesnt sedate me xxx

[Perinowpost]

Hi Discogirl

Utrogestan sedates me, therefore I take it last thing at night and it knocks me out. I can sometimes wake a few hours after this feeling very hot but usually get back off pretty quickly.

When I first take it I actually feel quite relaxed up until about day 4. Then very quickly it tips over into feeling blurgh i.ie., depressed, dizzy, confused, lethargic. It’s as if it builds up in my system and becomes too much. Hope this helps x

[Blue Kingfisher]

Hi discogirl, progesterone is also fine for me to start with and I also find it quite a relaxing tonic for the first few days but then, like Perinowpost, I start to feel dreadful. It feels like I’m walking through fog every day with heavy legs, foggy brain, exhaustion and depression. It also can make me hot at night, particularly when I start taking it and again, like Perinowpost, I often wake up a few hours later very hot and I also have palpitations sometimes.

Perinowpost, I hope you have a nice time away - good idea to postpone the progesterone trial! I lost count of the amount of things I’ve missed out on or ruined because of stupid hormones! How much oestrogen are you on out of interest and what type of you don’t mind me asking?

[Perinowpost]

I forgot about the nightmares Blue, yes it does give you those.

I am on evorel 50 patches, my body loves those. I don’t want to up the dose ‘cos I don’t want to have to take any more prog. I do change patch every 3 days though (and leave the older one on the extra half day).

Interestingly I have just had my annual scan which I have because the regime I follow is off licence. All was fine - womb lining is 3.3mm. This despite the fact I only use it x 7 days per month, and have only ever used it this way (because I literally can’t tolerate more) x

[Blue Kingfisher]

Just an update on this. I’m now a week in with no progesterone and no bleed. Feel so much better for stopping it, best thing I’ve done in months!

Perinowpost, how are you getting on?

[Perinowpost]

Hi Blue

I am about to start the Lutigest tonight . I’ll let you know how I get on x

[discogirl]

can i ask blue and perinowpost how much estrogen your on.

also blue if you only take prog 7 days a mth does that mean theres a chance you could be estrogen dominant.

sorry if i sound dim im still learning about hrt xx