Sorry to hear about your anxiety, I have it too. Unfortunately yes it takes time. For me, I feel good with every other symptom but anxiety is still there with all my HRT on right dose so it’s about waiting, using other techniques like meditation, CBT, magnesium at night, learning about breathing techniques and things like that. I know it is horrible, so you have my sympathies. Be patient though and try other things too. It can take 3 months or more to really be fully effective.