I think it's that rather than the tablet that's causing the agitation? However, three times now, I've had the tablets just fall back out and I'm not in any way spacious down there! Something's most odd all round! Because the applicator is not efficient, I am using a finger to insert and now quite sore with all the poking about. Back to Vagifem, which gave me no problems at all, soonest I hope! 🤞