Hi Eleanor, I saw you mentioned this, did some research and decided to buy some. It's mentioned in a couple of books I've been reading and also prescribed by the Marion Gluck menopause clinic in London. I've been taking 30mg transdermally for 4 weeks. I do feel a little clearer- headed, but it could be placebo affect. It certainly isn't giving me any side effects. I showed it to my GP who has a special interest in menopause and she thinks it looks positive. I also asked her opinion of DHEA and she said to toss that in the bin. I am going to buy a second lot when the first one runs out to give it 3 months. So far, so good.