It is so good to know I am not alone with this, but I was so hoping the HRT would help. I have just changed from Femoston 2/10 to oestrogel and utrogestan. I noted that I felt less anxious when I was taken the combined tablet (took it for 5 months), so am using the utrogestan everyday 25/28. Ironically, the week before I changed over following a private consultation with Dr Shaw in Cambridge, I had a really good week with very little morning anxiety, which meant I was also much happier and able to look forward to my day. I did wonder if I should change from the Femoston, but the week before I had been really bad and judging by comments on this thread there seems to be no pattern to this anxiety. Only on day 4 of new regime and have been waking early and anxious for the last 2 days, but mood has not dipped as low as before I started HRT. I just hope once I have got used to the new regime it will fade again. IT really is a horrible feeling and colours everything I do and makes me feel discontented with every aspect of my life and worried about upcoming events that I should be looking forward to. Sending hugs to all that suffer xxx