Hope it works for you Annie. My dose was increased from 1 tab x 3 nights a week to 2 tabs x 3 nights a week, one up one down (about an inch in), but chose instead to do 1 a night for 6 nights, alternating sites, as I seem to sleep a bit better on Vagifem nights! So you could try whatever is most convenient for you. Have just been authorised to stay on 5-6 a week long term, so breathing a sigh of relief that this may finally get things back to some version of normal!