Hi, Alesia!
YES!!!!!! The difference with the Oestrogel/Estrogel and Oestrodose has been remarked upon on these forums and when I used the Oestrodose, I noticed it was slightly more watery - on 2 pumps, I didn't feel the same as I felt on 2 pumps of Estrogel previously (and I developed a rash on Oestrodose that I didn't have with Estrogel).
I think folk thought - oh, here goes Tempest again!
But - a few others starting noticing well after the thread I posted was 'dead and buried' on the forum too! I can't remember who, but someone contacted Besins and they confirmed that the Oestrodose is bulk product that is then repackaged by various distributors in the UK (its cheaper that way).
Another lady had to increase her dose by one pump to get the same effect as she had from her previous dose too on another separate thread.
So - I would say its WELL worth upping your dose just to see! Or, you can try sourcing Estrogel, but your prescription would have to state Estrogel specifically (GP's seem to be issuing prescriptions for 'estradiol gel' which means you could get anything).
The pharmacy in London which issues private prescriptions only for Professor Studd always carries Estrogel, so I've been told by another lovely member here.
I'm thinking this is a case of more 'short changing' in the NHS on prescriptions, but its rubbish if the generics don't work as well!
You may notice a difference, so it's worth as try! Give it a go. By the way, Professor Studd usually prescribes 3 pumps for ladies in surgical menopause at least (I had a prescription from him last year which stupidly I didn't fill. Its now expired)!
And also.....one eighth of a sachet of Testim daily. If you haven't tried this, I'd ask for a prescription - it could make a big difference to you as you lost 75% of your Testosterone when you had the oopherectomy and with age, the input from the adrenals declines (that adrenopause again) so it could be why you're feeling so awful! Don't forget, although your lovely Kiniesologist had POF, she wouldn't have lost androgen or estrogen input completely and abruptly as you have, so you're a special case in comparison.
If you want to read about Female Androgen Deficiency Syndrome to see if the symptoms fit you, Professor Studd has published papers on this and you can also find other articles on the web.
I hope this gives you a couple of things to try!
Hugs! xxxxx