Hi edelweiss
from me too.
Sorry to hear you are feeling rough.
I was just wondering how you can say you are post-menopausal if you were peri when you started hRT? You will only be able to tell this if you stopped HRT and waited a year and then if no periods you would be post-menopausal. However if you were very late peri-menopause when you started HRT in 2012 it is likely you are post-menopausal now.
It is surprising for you to suddenly experience low mood and if you are not experiencing flushes and sweats it may not be down to the oestrogen at all. You say you have lost weight as well so if this has happened without trying and without a change in diet or much change in exercise then you should really see a doctor and ask for an explanation. Those oestrogen levels are good ( depending on when they were taken).
Re taking ADs - is there any reason ie recent life events/experiences which would lead you to experience low mood? Personally, if not I would want to seke out other reasons before going down this route - eg maybe another endocrine problem ( ref weight loss).
Also the other thing is that oestrogen levels fall on average for two years following the last ovulation until they reach their lowest level ( approx - as there can still be some minor activity) - so you could be experiencing the effects of this - even though flushes have not reappeared?
Also how do you take the Provera? Is it continuous or do you have a withdrawal bleed? Some women experience continuous low grade side effects from progestogens - although if you have taken it this way for several years it does not explain the recent change (although our bodies do change over time!). However something to think about - you could try going back to a cycle (with the OK from your doc) - and see how you feel on oestrogen only?
Hope this helps a little!
Hurdity x
