For those interested in Menostar: from the (Bayer) manufacturer info ( I put the asterisks to delineate their recommendations re: progestin )
2 DOSAGE AND ADMINISTRATION
Generally, when estrogen is prescribed for a postmenopausal woman with a uterus, a progestin should also be considered to reduce the risk of endometrial cancer.**** It is recommended that women who have a uterus and are treated with Menostar receive a progestin for 14 days every 6 to 12 months and undergo an endometrial biopsy at yearly intervals or as clinically indicated in order to detect any endometrial stimulation which might require further clinical action. A women without a uterus does not need a progestin. ****In some cases, however, hysterectomized women with a history of endometriosis may need a progestin [see Warnings and Precautions (5.2, 5.14)].
Use of estrogen-alone, or in combination with a progestin, should be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman. Postmenopausal women should be re- evaluated periodically as clinically appropriate to determine if treatment is still necessary.
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14 days once or twice a year is not too bad IMO, but it may not be enough estrogen to treat symptoms as it is formulated for osteoporosis
A