Interesting article, particularly re. abnormally high oestrogen (over 200 pmol) causing anxiety etc. via the adrenals and how progesterone therapy makes things worse initially by raising oestrogen for a full cycle before it starts to oppose the oestrogen. Also how oestrogen surges more in the 2nd half of the cycle when it's an annovulatory cycle, making it appear that progesterone is causing the anxiety.
Interesting to hear from anyone who is peri and not getting the obvious low oestrogen hot flushes etc. who has put themselves through a month of prog therapy hell to come out the other side! Although I suspect most would give up and assume they need oestrogen instead.
www.cemcor.ubc.ca/resources/perimenopause-time-“endogenous-ovarian-hyperstimulationâ€
(Sorry can't the link to go auto as doesn't like the "", so please cut and paste)