It might be because I was getting headaches towards the end of week two, whilst just on the oestrogen. I get hormonal headaches but these were real corkers lasting for days. Would oestrogen cause headaches do you think? My headaches have always been premenstrual in the past. I am 51 and was still having periods all be they a bit irregular. No hot flushes just generally becoming moodier and moodier. I do have some 50mg patches left and have been bunging one on at the end of week two when there would usually be a drop in oestrogen levels. I might ask her to up the dose to 50mg though in a few months, when we see how the Utrogestan works out. She admits to knowing very little about HRT but at least has the Grace to admit it and look stuff up! Thanks