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Administration:
Blissel has to be applied into the vagina using a dose-marked applicator, following carefully ?Instructions for use? included in the information leaflet, and below.
One applicator-dose (applicator filled to the mark) delivers a dose of 1 g vaginal gel containing 50 micrograms of estriol. The filled applicator should be inserted into the vagina and emptied, preferably in the evening.
To apply the gel, lie down, with knees bent and spread apart. Gently insert the open end of the applicator deep into the vagina and slowly push the plunger all the way down, as far as it will go to empty the gel into the vagina.
After use, pull the plunger out of the cannula and then, accordingly with the presentation, you may clean or reject the cannula as indicated in ?Instructions for use? included in the information leaflet.