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Author Topic: Progesterone intolerance  (Read 633 times)

Helenmelon1974

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Re: Progesterone intolerance
« Reply #15 on: July 05, 2024, 05:57:26 AM »

Hi Helenmelon

Sorry to hear about losing your partner.

Re HRT - try not to be anxious nor read about problems that others have had. I have hardly had to do any tweaking and have been on HRT since I was about 54, now 71. Mostly on the same regime which has been oestrogen patches and vaginal utrogestan (though initially cyclogest off-licence, before Utrogestan was available). However I have almost always taken it on a cycle and wouldn't relish the thought of DAILY vaginal oestrogen. I do find it irritates my bladder when I am on that phase of the cycle - eg getting up for night time pee, as well as some irritation of labia (I do use vaginal oestrogen too - vagirux and estriol 0.01%).

I would be interested to hear of women on here who are taking it daily, vaginally.

Previously for a very short time I used Evorel conti but gave me headaches. Utrogestan is bio-identical, yes but is taken in larger doses than the synthetic progestogens so is not without side effects - so do be prepared for these - though do not worry! Progesterone is a sedative so you may feel tired, but you may well find 200 mg is tolerable. Many women take 100 mg daily orally without issues.

As for giving up HRT - you haven't said your age nor menopausal stage but I'm guessing from your name you may be 49 or 50? That being the case - you would be too young in my view not to think about HRT, as you are still not at the avergae age of natural menopause in the West (51/52) and even so we may live to our 90's so that's a long time to be in an oestrogen deficient state!

Some GPs maybe prescribe testosterone but as it's off-licence ( there are no licenced UK testosterone preparations for women so we have to have T products made for men which are stronger) they may not. The NICE Guidelines made provision for T prescription in cases of low libido when on adequate HRT - (but oral HRT also affects - can reduce libido/response) but it is really up to the GP/practice.

I had to see a private specialist initially in 2015 - but this was before the NICE Guidelines, but thereafter my very enlightened gynae specialist GP agreed to continue prescribing it and it has been on my repeats since then. You shouldn't need a blood test although a baseline test is helpful. T tests are inaccurate at very low levels as the tests are designed for the T ranges experienced by men so not sensitive enough for women - though they are the best we have!

Hope this helps

Hurdity x

Following my last reply to you I’ve actually come on my period! So I’m still in peri? I’ve had an Evorel 50 on since yesterday so when would I introduce the Utrogestan? Is it supposed to tie in with you own cycle? So confused 🤣

Sorry to be a pain!
Helen x
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Penguin

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Re: Progesterone intolerance
« Reply #16 on: July 05, 2024, 08:01:33 AM »

Would I need to adjust the dose? I’m not 100% sure it is the Utro but I’ve been feeling sick a few days after I started it so assuming

No, I was told it is the same dose as they can't guarantee level of absorption. The issue for me is the need to take orally on an empty stomach, I can't do that on any medication due to having had gastritis. Nausea is one of the potential side effects of oral use, although equally it could just be hormonal fluctuation. If it has only been 3 days perhaps give it a bit longer to see if it settles. I had nausea in peri well before I started hrt.
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Ebonybones

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Re: Progesterone intolerance
« Reply #17 on: July 05, 2024, 03:52:26 PM »

Thank you it’s settled today so hopefully that’s it and it wasn’t hrt related
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sheila99

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Re: Progesterone intolerance
« Reply #18 on: July 05, 2024, 05:34:41 PM »

If you're on cyclical utro you take it days 15-26 where day 1 is the first day of your bleed.
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Helenmelon1974

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Re: Progesterone intolerance
« Reply #19 on: July 05, 2024, 06:29:11 PM »

If you're on cyclical utro you take it days 15-26 where day 1 is the first day of your bleed.

Thank you ☺️
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Hurdity

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Re: Progesterone intolerance
« Reply #20 on: July 06, 2024, 09:08:29 AM »


Following my last reply to you I’ve actually come on my period! So I’m still in peri? I’ve had an Evorel 50 on since yesterday so when would I introduce the Utrogestan? Is it supposed to tie in with you own cycle? So confused 🤣

Sorry to be a pain!
Helen x

Yes if you had your Mirena removed in April and you are bleeding and not on anything else - then it is likely you are still peri-menopausal.

Use Utrogestan as per sheila99 but if you are late peri, you won't have much of a natural cycle and your HRT cycle will be an artificial one - and since you don't know what your natural periods will be doing then sensible to tie the HRT in with your bleed.

All the best

Hurdity x
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