whoops went off on it's own, the last post!
Anyhow, after chemo etc...I was very shattered anyhow for years so I genuinely find it difficult to equate HRT with the benefits. Oesteoporosis runs in my family and biophosphonates do not work, so chose to remain on HRT rather than get even worse physically. As I mentioned my last implant, of E only, was renewed after 15 mths and my e levels were still around 450pmol. I do seem to retain the benefit of the implant for a long time, however I also seemed to have more energy prior to the latest implant.
I felt taking the T implant, made me very flat but 'I' believe this may have more to do with potentially supressing the adrenal glands, etc... in susceptible people like myself. When I introduced androfemme for the last two months of my last implant my energy levels, mood, sleep etc... was great. Then after the implant it all reversed. So, I really have no clue. I think there are so many interactions that occur in the body with the introduction of exogenous hormones, i.e. that effect the immune system, the adrenals, thyroid etc... it really is very difficult to work out what actually is the MAGIC formula is.
Oestrogel was v strange for me, I did not absorb well and my estrogen level was around 250 pmol. I do believe I had more energy though at the lower level.
I know the above is not very helpful but I find it difficult to work out what the magic formula is and due to oesteoporisis in the family etc I intend to remain on HRT . I had other problems before renewing the implant, i.e. hot flushes etc.. but energy, mood wise I was much better.