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[joziel]

Elaine, what dose of Oestrogel are you on - and have you had bloods done on that dose?

When you say it's the progesterone causing the problem, how do you know that (if you are taking it every day)? Have you tried stopping the progesterone to see?

Too high estrogen dosages (for you) can cause insomnia and just feeling wired and anxious. Some women do get that from progesterone, but it's much less common.

If it is the utrogestan causing that and you have endo, you can try other synthetic progestins which you might get along better with. Norethisterone and desogestrel for eg, are both systemic progestins. You could also try a combined patch which has another synthetic progestin in it.

It's a bit premature for people to be suggesting powerful meds like anti-depressants etc IMO. The objective has to be to help people get their HRT sorted so they have no symptoms and don't need all these meds women used to need prior to HRT...

[sheila99]

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I also found it made me feel calmer, whereas oestrogen only makes me feel rather anxious.

Too much as well as too little oestrogen can give you anxiety. Have you tried lowering the dose a little?

[Elaine90]

Hi thanks for all the replies

I'm going to have a review in a month and will bring up the possibility of trying femostan then if that fails will ask GP about low dose amitriptyline or similar.
sheila99 - I agree too high or too low is bad, but found any amount of oestrogen when taken on it's own causes anxiety, it's ok with testosterone though (probably because the oophorectomy left my T levels too low in relation to E, in natural menopause it's usually the other way around)

The HRT has helped the long term physical deterioration cause by the surgery, but every day since starting it, I'm firefighting symptoms and wondering have I taken too much, too little, the wrong ratios...it doesn't help that I'm oversensitive to small changes and that the different products (oestrogel, testogel, Utrogestan) have different durations, so they go out of balance. And if I try to stop or cut back, I get withdrawal symptoms. All in all, not great.

[Elaine90]

Joziel thanks for the reply.

It's a long story as I've been trying to figure this out for 10 months, essentially:

Oestrogel 2 pumps (built up slowly over a number of weeks) I've had bloods done and on oestrogen only I could sleep, but after a couple of months started to get endo pains.

The first time I took Utrogestan 100mg, I felt wide awake all night, not stressed, just couldn't sleep the entire night.
Tried various methods and doses (slowly, methodically, over a number of months) - in the morning; vaginally; half a capsule; a quarter of a capsule; with extra oestrogen.
I found that the less Utro I take, the better my sleep is, but that I get withdrawal symptoms (like PMS) as it not enough to reach a steady state. Maybe it shouldn't happen, but it does, I must be very sensitive to fluctuating levels.

Discussed with the gynae who suggested Evorel Conti (with Norethisterone) - this felt great, but also caused insomnia and my hair started to fall out.

The testogel also causes insomnia if I take it too late in the day or have too much. I'm OK with around 1/8th sachet first thing in the morning, that seems to build up over time, so sometimes have to cut back.