Is there a reason to take ads rather than increase hrt? If it's caused by oestrogen deficiency then the appropriate treatment is to replace the missing oestrogen. My anxiety was purely from oestrogen deficiency, it arrived with peri and went with hrt. I've had to increase twice because anxiety and insomnia returned and am now on 100mcg which has it completely under control. I was offered ads instead of hrt but refused. To answer the other question about utrogeston 100 daily is sufficient for 100mcg oestrogen. 211 is low, on that level some peri symptoms wouldn't be unexpected. I think they like it to be over 300 to protect your bones. Sorry i haven't answered you question, I don't know about Fluroxetine.