It's so hard for us wome. I was prescribed Sertraline in my late 40 for severe pmt. I know think it was because I was peri. Post menopausal 5years on an feel utterly exhausted both mentally and physically, not to mention emotionally. My HRT journey began on normal cyclical regime but it became apparent that my mood was becoming lower and lower. At that point I was so low and scared that I decided to seek help from a private menopausal specialist. Within 10mins of us chatting she suggested I may be sensitive to progesterone. My regime changed to evore plus utrogestan. For the first few months I felt amazing, just like the old me. Then my mood plummeted. My gp still to this day is insistent that I am depressed and not hormonal. I am taking 200mg Sertraline daily now. I am currently trying utrogestan 200mg vaginally and it's only a few weeks in. I'm so tired and a few weeks ago around my birthday had a meltdown. Sobbing, feeling useless worthless and just genuinely miserable. I just didn't see the point anymore. My gp and specialist say that I would be a great candidate for the mirena. Why does every alternative fill me with dread. My mood is slowly getting better. But I'm still tired and emotional. My aunt said to me yesterday when are we going to get you back. And I'm sure my partner thinks that too. I want me back. But not sure how long I can keep truing all the alternatives. This is such a wonderful forum gull of strong women who deserve to feel themselves again. Knowing there's women who are experiencing the same issues helps immensely. Hopefully we will all.get there xxx