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Author Topic: Progesterone Intolerance  (Read 2190 times)

Tribbins

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Re: Progesterone Intolerance
« Reply #15 on: October 06, 2023, 05:44:44 PM »

Mary G, do you know where scans can be done? Is it private clinics?

I've heard ultrasound direct mentioned on here. They do a wellwoman pelvic scan which is transvaginal and it is £145. Seems you can get an appointment really quickly too. Their TrustPilot reviews are very good.

I've checked this out, there's one in my nearest town. I'm going to do oestrogen only until my next review in a couple of weeks then get a scan. I can't even cope with 50mcg progesterone every other day, just too crappy feeling. I tried to reduce oestrogen and migraines come back, feel between a rock and a hard place at the minute. There's got to be some solution.
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Mary G

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Re: Progesterone Intolerance
« Reply #16 on: October 06, 2023, 07:18:21 PM »

It sounds like Watson/Savvas have bowed to BMS pressure on progesterone doses so there is no point in going to them.  If you are progesterone intolerant, you will never cope with that dose.

A Mirena coil is a definite maybe but again, if someone is diagnosed as progesterone intolerant, it's not going to fly.  Although the progesterone from the coil is mostly confined to the womb, enough of it can reach your overall system and cause side effects like breast pain in my case. 

A progesterone coil with a lower dose than the Mirena (Jaydess) is worth a try.  It's not licensed for HRT use (only contraception) but there is no reason why you can't try it as long as you have regular scans.  I found the Mirena caused too much thinning of the womb lining so if you can swing the Jaydess, it could be a good option.

Once you have tried all the conventional progesterone routes, the final port of call prior to the last resort (hysterectomy) is compounded progesterone.  The Specialist Pharmacy in London who produce it can provide a list of all the practitioners who prescribe their products.  I got on well with progesterone lozenges @50mg but they now have drops and creams that are also very good and very effective on the endometrium.

For the record, I'm not progesterone intolerant!  I did think I had suddenly become so post menopause because the Mirena coil, Utrogestan and all other forms of synthetic progesterone triggered my silent migraines but it turned out that the dose was just too high and I how happily take 50mg progesterone every day with zero side effects.

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Ama

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Re: Progesterone Intolerance
« Reply #17 on: October 07, 2023, 08:12:07 AM »

Hello ladies. Thank you so much for sharing your experiences on progesterone. I am on vaginal Utrogestan 200mg for 12 days of the month. The 1st month was ok but now on day 5 of the second month and I am experiencing anxiety and low moods. I’m also on AD which has been helpful but does not seem to be helping with my progesterone anxiety. Please can anyone suggest any herbal remedies which can help with anxiety? It’s all very debilitating and I really don’t know what to do. I would appreciate your responses, please.  Many thanks. 
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jorainbow

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Re: Progesterone Intolerance
« Reply #18 on: October 07, 2023, 08:29:00 AM »

I think you will struggle to find sonething you can take alongside AD'S.  Definitely not st johns wort or rhodiola. Maybe try a magnesium supplement?
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Penguin

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Re: Progesterone Intolerance
« Reply #19 on: October 07, 2023, 08:44:02 AM »

It sounds like Watson/Savvas have bowed to BMS pressure on progesterone doses so there is no point in going to them.  If you are progesterone intolerant, you will never cope with that dose.

A Mirena coil is a definite maybe but again, if someone is diagnosed as progesterone intolerant, it's not going to fly.  Although the progesterone from the coil is mostly confined to the womb, enough of it can reach your overall system and cause side effects like breast pain in my case. 

A progesterone coil with a lower dose than the Mirena (Jaydess) is worth a try.  It's not licensed for HRT use (only contraception) but there is no reason why you can't try it as long as you have regular scans.  I found the Mirena caused too much thinning of the womb lining so if you can swing the Jaydess, it could be a good option.

Once you have tried all the conventional progesterone routes, the final port of call prior to the last resort (hysterectomy) is compounded progesterone.  The Specialist Pharmacy in London who produce it can provide a list of all the practitioners who prescribe their products.  I got on well with progesterone lozenges @50mg but they now have drops and creams that are also very good and very effective on the endometrium.

For the record, I'm not progesterone intolerant!  I did think I had suddenly become so post menopause because the Mirena coil, Utrogestan and all other forms of synthetic progesterone triggered my silent migraines but it turned out that the dose was just too high and I how happily take 50mg progesterone every day with zero side effects.

Thanks Mary G that is really really helpful. I will try and find out more about the Jaydess and where I might be able to get it. Do you think I'd still need scans if I went down that route?

I have not heard about compounded progesterone before. I will look into that too. At the moment I am feeling the usual horrible drop that always happens when I stop taking the utrogestan, even though I only took 100mg on the last night - feeling very down, anxious and full of rage all at the same time 🙄
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Mary G

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Re: Progesterone Intolerance
« Reply #20 on: October 07, 2023, 11:39:49 AM »

Penguin, I found a fact sheet from the Chelsea and Westminster menopause clinic and there is a third coil (Kyleena) which is also low dose. They recommend the Jaydess and the Kyleena off licence for progesterone intolerant women with annual/biannual scans.

https://www.chelwest.nhs.uk/your-visit/patient-leaflets/medicine-services/levonorgestrel-intrauterine-system-with-hormone-replacement-therapy



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sheila99

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Re: Progesterone Intolerance
« Reply #21 on: October 07, 2023, 11:54:01 AM »

Have you tried different types of progesterone? Just that sometimes it can be intolerance to a formulation so it's possible you might find something you tolerate better. I know it isn't the same but I'm wiped out on utrogeston but fine on norethisterone (which I can't have now because of of allergy to something else in it).
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Penguin

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Re: Progesterone Intolerance
« Reply #22 on: October 07, 2023, 12:31:57 PM »

I have only tried utrogestan. I thought itd be the same on all types unless I had a lower dose. I really liked the sound of Dydrogesterone but don't really want to stop the estrogel as I really like it.
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Ama

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Re: Progesterone Intolerance
« Reply #23 on: October 07, 2023, 12:35:32 PM »

Thank you @ jorainbow. I will try magnesia supplements. I hope I get some relief. Many thanks for replying. 
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bubble tea

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Re: Progesterone Intolerance
« Reply #24 on: October 09, 2023, 04:18:18 PM »

thank you everyone for the advice - I feel as if I have a lot more options and places to look now
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AKatieD

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Re: Progesterone Intolerance
« Reply #25 on: October 12, 2023, 10:28:02 PM »

I can' t take Utrogestan either but am fine on Crinone (another progesterone that is bio identical to the natural one), which comes as a vaginal gel. Different formulations of the same compound definitely affect us differently.
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AngelaH

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Re: Progesterone Intolerance
« Reply #26 on: October 12, 2023, 11:03:50 PM »

I have been recommended the mirena coil also but because my reaction to Utrogestan was quite severe I am scared to try it.
I am perfectly fine with mirena coil, but can’t tolerate utrogestan. Those two products are different types of progesterone and for some reason my body prefers synthetic one.
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