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Hi Pepperminty, I've been on 2 pumps gel with utrogestan for 4 years now, that has helped hot flushes but not joint pain or anxiety. Am 67, 12 years post meno.I have now decided to increase to 3 pumps to see if it helps with this. I thought I would try it for 3 months. Gp is doing blood tests and mentioned anti d's for anxiety and joint and muscle pain but not sure want to go down that route.I guess we're all different and can only try!