Exactly Flossieteacake. It is very safe or it wouldn't be prescribed. I had breast disease in the 1990s and my GP never hesitated in suggesting it. To keep symptoms under control, use as much and as often as is necessary.
I've had ovestin for several years, into the vagina with the applicator, squeeze and withdraw. Wash applicator. When necessary either a little smeared around the vulva or KY jelly there.