I’m new here and still finding my way round. Saw your mention of prolapse which I have too plus the joy of haemorrhoids!! Was prescribed Vagifem and this helped a lot but didn’t like breast pain and cramps in legs, which may have been coincidental, so I stopped using it. GP said it would be okay to just use once per week in my circumstances but what I don’t get is all the discussions around dosage etc. and the fact that it is supposed to just work locally and not systemically. My question would be then, if it’s only working locally how come this brings on leg cramps, breast pain, thinner hair, weepiness etc? Doesn’t add up to me and as I’m struggling alone with this I joined this forum in the hope of finding someone who is having similar doubts but also has similar symptoms. Haemorrhoids are a taboo subject despite the fact that when you research online you are told 1 in 3 people has them but I don’t know anyone at all that has them!! Just hoping to get some feedback and experience from others - that would be so useful.