It is also worth considering if there are other contributory factors, such as diet effects, (high carbohydrate, high sugars), alcohol, caffeine, other stresses.
Then worth considering other non hormonal options rather than increasing estrogen, such as Cognitive Behaviour Therapy–the fact sheet on WHC is excellent–https://www.womens-health-concern.org/wp-content/uploads/2023/02/02-WHC-FACTSHEET-CBT-WOMEN-FEB-2023-A.pdf
If there definitely seems to be a need for higher dose estrogen, then Evorel conti can be used as one and half patches--it is not licensed to be used this way, but we believe that the 2 hormones estrogen (the main part of HRT), and progestogen (needed to prevent estrogen from stimulating the womb lining), are evenly distributed across the patch and so should be ok to use in this way. Not ideal but probably better than separating the estrogen and progestogen
Best wishes