Hello Polly,
I am much the same as you. 6 months on estradot 50, felt a bit better, more steady, then dipped low again with symptoms getting worse again.
I have just increased yesterday to 75... But I was worried it would be too much too soon. So I have snipped a tiny bit off a 75 to get about 62 increase. Going gently to get my body gradually used to an increase before hitting the 75.
the patch does not stick so well for me, so a bit of micropore tape helps. Seems like a few ladies cut their patches as well?
Someone I know said yesterday she was in a bad way and went straight from 50 to 100. Hard-core girl. But the g.p was ok with her. It is so individual all this tweaking.
Wish you well