Hi Slinks, I was on Oestrogel for over 25 years and then they slightly changed the formulation and it really did not suit me and when I had a blood test the Meno consultant said I might as well not be on HRT at all as I was not absorbing it at all for me I had to change to patches. I felt really unwell on it, headaches, nausea very groggy, dizzy, insomnia and palpitations but hardly surprising as I was not absorbing any of it. However all the previous years I was on it I was absolutely fine and I know lots of people who it works really well for. Very often it takes quite a while for your body to adjust to HRT so hope so much you start to feel better soon xx