I’m similar to many of you and change every 3 days.
Estradot (at the moment, no idea if I’ll get the next lot!) 125 and put them near pubic triangle, alternating sides and away from a skin fold (when I sit if that makes sense!) was going to trial 3.5 days on this higher level though I find it easier to remember to change in the mornings.
I’d wondered similar previously when on 100 and placed it slightly higher up where there’s more fat. Unfortunately forgot that’s when I had a blood test. No idea if it affected it or if that was my actual level but oestrogen was around 200, whereas on 75 it had been 260.
Either way Gp (nhs but v good) was happy to go higher by 25 - I think if it had been double that she wouldn’t. She said it was slightly outside prescribing guidelines but obviously test showed it was ok.
I’d actually gone querying testosterone; she had tested that and has prescribed too.
So I now stick to where I’d been putting them, roughly under where pants go. I know everol do say bottom whereas estradot state lower tummy -I put everol there too. Though bigger it still works as they seem more flexible.