Positives: all my symptoms vastly improved or virtually non-existent (Poor sleep, no energy, a weird all over body inflammation, especially at night, joint pain, dryness of all mucus membranes, VA, brain fog, emotions all over the place - would cry at the slightest thing, inability to regulate body temperature, loss of sex drive, thinning hair, the feeling that someone is sticking pins into my arms and legs, like nerve zaps)
Negatives: initially Evorel Conti caused bleeding that got more regular and prolonged over time (I’m post meno) so switched to Evorel 50 and Utrogestan. Things seem to be improving now, not quite there yet, but it’s looking positive.
I took a 2.5 year break from all HRT except Vagifem. ALL symptoms gradually returned, until I could stand it no longer. When I went back on HRT the improvement was dramatic. Within 5 hours I felt my head clearing. I feel brilliant on it. For me, the quality of life far outweighs any risk factors.