I did the first week on the 50's then I've been on the 25 since then. The breast tenderness came last month for a day or so, this month is been a week of 'don't touch me!!', to the point where I've taken off the patch. As you say, I was thinking of cutting off a chunk but then I wondered what the point would be of that small a dose and it made me question coming off and seeing how I feel. I feel like I had limited reasons for going on to start with and now side effects make me wonder if actually I was depressed, not menopausal, or only a tiny bit reduced in my oestrogens because of stress. I've taken significant steps to deal with the stress other than the HRT.