You can get anatomical saddles for women with strategic cut-outs & great big padded armchair-like jobs for comfort too, but not sure whether compatible with the seat posts on an electric bike. I used to cycle regularly for some years after VA developed & it didn't create additional probs for me, but VA has worsened recently & I no longer cycle due to fears of coming off & breaking a bone (osteopenia). I do use an exercise bike indoors, but only for 10-20 mins at a time, so nowhere near like time spent out on a road bike. Hopefully others will be along soon to give their experiences.