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Author Topic: Hysterectomy for progesterone intolerance  (Read 2153 times)

Mag22

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Hysterectomy for progesterone intolerance
« on: July 22, 2022, 10:11:01 AM »

Has anyone considered or had a hysterectomy so they can just take oestrogen safely?
I’ve tried all options for progesterone and I cannot do it.
However with nothing I ache all the time I’m low in mood and weepy and so tired there seems little point in carrying on.
My gp is sympathetic but clueless.
I’ve read all I can but being so brain foggy I just feel overwhelmed.
Do the nhs offer this option?
I’m done with this.
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Nas

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Re: Hysterectomy for progesterone intolerance
« Reply #1 on: July 22, 2022, 10:24:15 AM »

Sorry to hear you are struggling.
Have you tried a mirena coil or similar (some release even lower doses of prog, than the mirena).
What symptoms do you experience on prog?

Maybe ask for a referral to a MS for advice, or a good gynae?

I did consider a hysterectomy last year, but was told no, largely because there is nothing wrong with my womb.
I was then pretty much pushed into the coil, which so far hasn't afffected my mood too badly.
If it doesn't work out, I will be in the same boat as you, as utrogestan doesn't sort my bleeding caused by HRT and I don't appear to be allowed to trial any others. Without oestrogen, I am weeing every half an hour and life becomes hell.

Best of luck.  :)
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joziel

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Re: Hysterectomy for progesterone intolerance
« Reply #2 on: July 22, 2022, 10:25:13 AM »

Some people have done this, but it is a pretty extreme solution. Your uterus provides a lot of 'structure' in your abdomen, so removing it can make you more predisposed to prolapse.

What are all the options you've tried for progesterone? Maybe someone can think of something else you haven't yet tried...
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Nas

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Re: Hysterectomy for progesterone intolerance
« Reply #3 on: July 22, 2022, 10:27:57 AM »

Cyclogest?
Provera?
Norethistone?
Mirena?
Utrogestan (vaginally)
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Gnatty

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Re: Hysterectomy for progesterone intolerance
« Reply #4 on: July 22, 2022, 10:41:50 AM »

There is a hysterectomy Facebook group which I think if you searched would find quite easily. It is quite heavily populated with women who have had hysterectomies for this very reason. I bet you will find lots of info on there. Re more likely to have prolapse, well you can make sure you limit the risks. Just being on oestrogen will make a huge difference plus pelvic floor exercises etc, not straining on the loo....
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CLKD

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Re: Hysterectomy for progesterone intolerance
« Reply #5 on: July 22, 2022, 10:51:21 AM »

A friend underwent hysterectomy and it changed her Life for the better.  It is major surgery.  You may require HRT support after, so discuss options B4 signing the Consent Form ;-).

A dedicated menopause clinic mayB better than a gynaecologist as they are almost as clueless as some GPs.

Don't despair.  Rest as much as you are able.  Keep eating, little and often which helps any anxiety surges.  Which symptom would you currently like to improve ?
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Mag22

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Re: Hysterectomy for progesterone intolerance
« Reply #6 on: July 22, 2022, 11:32:34 AM »

I’ve tried oral progesterone and became seriously suicidal so am petrified at the idea of a coil I can’t get rid of quickly. I seem to be very sensitive to both oestrogen and progesterone the oestrogen makes my mood better but I get cramps in womb and bleeding and generally swell up with fluid retention. Even herbal alternatives seems to cause similar symptoms I did have severe PMDD and felt better when pregnant so seems I dont get on with my own body 🙄
I don’t know what to do next really I already have osteoporosis and at 58 I don’t have much longer to try hrt.
Will look at the Facebook group and see what people ‘s experiences are.
It might be I just manage the symptoms I have and ignore the cause! Bloody hormones. 
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CLKD

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Re: Hysterectomy for progesterone intolerance
« Reply #7 on: July 22, 2022, 11:34:05 AM »

Have a look too at the UK based osteoporosis support group.

Make notes ;-)

I wonder which hormone made you feel well during pregnancy .......... that would be your answer?
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joziel

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Re: Hysterectomy for progesterone intolerance
« Reply #8 on: July 22, 2022, 01:00:25 PM »

Mag, if you have osteoporosis you really ideally need to figure out a way to get some estrogen in there.

When you say you 'tried oral progesterone', which did you try? Body identical utrogestan? Did you try using that vaginally? You do know you can use the same capsule in your vagina instead and not have to take it orally?

There is also Provera, which is a synthetic oral progesterone you can take. There are two different patches, with different progesterones in them (Evorel Conti and FemSeven Conti).

And then there is the coil. I understand being freaked out by not being able to remove it, but surely if you saw a doctor and explained that you were considering a hysterectomy before trying the coil, because you were afraid of not being able to remove the coil ASAP, then surely they would agree to remove it as soon as you asked? The alternative is a huge surgery. If they won't remove it, try different doctors, go to A&E or see someone privately - you get what you ask for when you go private. Which is all to say - I don't think you should be so afraid of the coil not being able to be removed that you don't even try it, and have a surgery that carries risks...

PS - it might be worth seeing a specialist menopause GP privately, because these are the situations they can be really good at negotiating, more so than regular NHS GPs.
« Last Edit: July 22, 2022, 01:05:30 PM by joziel »
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Evie606

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Re: Hysterectomy for progesterone intolerance
« Reply #9 on: July 22, 2022, 04:09:13 PM »

Has anyone considered or had a hysterectomy so they can just take oestrogen safely?
I’ve tried all options for progesterone and I cannot do it.
However with nothing I ache all the time I’m low in mood and weepy and so tired there seems little point in carrying on.
My gp is sympathetic but clueless.
I’ve read all I can but being so brain foggy I just feel overwhelmed.
Do the nhs offer this option?
I’m done with this.

Hi Mag,

I’ve had serious issues with all progesterones and I’m on the last option. As I’ve previously had endometriosis, I was told hysterectomy would be the next option (on nhs) but I was also warned it’s major surgery and I’m not too keen tbh.

Can you see a private consultant? Some progesterones are only available privately or with the guidance of a specialist. My gp was limited with what she could give me.

Have you tried Crinone? It didn’t suit me but consultant told me it’s been popular amongst the intolerant. Bijuve combo tablet was also mentioned.
I’m currently 7 days into Cyclogest on a Conti regime and am tolerating it well so far but will see how I go over the next 4-6 weeks.
Hope you find another option to try. X
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Ecl

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Re: Hysterectomy for progesterone intolerance
« Reply #10 on: July 22, 2022, 06:52:47 PM »

Hi, there is a patch which I believe contains the same progesterone as the coil, however it ( as with all) can be quite tricky to get hold of, I believe it’s femseven. It may be a way for you to try it without a long term comittment.
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joziel

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Re: Hysterectomy for progesterone intolerance
« Reply #11 on: July 22, 2022, 08:19:08 PM »

Although the patch would get more into the system and affect someone more than the much lower amount applied only locally in the coil, so it might not be a fair way to judge what would happen with the coil...
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Mag22

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Re: Hysterectomy for progesterone intolerance
« Reply #12 on: July 23, 2022, 10:15:13 AM »

To be fair I didn’t try utrogestan vaginally and I take your point about establishing a quick removal route for the mirena and also made sense to try that before moving to major surgery as I know that’s no fun have already had both ovaries removed   
Will go back to doc look into a menopause specialist and be a bit braver about having another go. I’m so miserable anyway I’m thinking of antidepressants but that’s a sticking plaster really, not going to solve the underlying issue.
Many thanks for your replies really helpful.
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Mag22

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Re: Hysterectomy for progesterone intolerance
« Reply #13 on: July 23, 2022, 10:19:18 AM »

Evie606 would you post how you get on with the cyclogest? As you are so intolerant it would really be worth knowing if you find something tat works.
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joziel

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Re: Hysterectomy for progesterone intolerance
« Reply #14 on: July 23, 2022, 10:23:03 AM »

Mag I know it really sucks but it's best to be really systematic about it - try one thing, give it enough time to settle, move onto the next... and so on.
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