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[Nas]

Absolutely Sheila
If only we could just go into Boots and pick and choose what we wanted for 0£ , 0 questions and 0 hassle.. bliss

[pepperminty]

Hi ladies,

there are loads of estrogens to try- but not many progesterone. There is the issue, i believe.

 Also, as Floradora says your reactions can change over time. I know some ladies on here who have been " P " intolerant and then later on have found it OK. The trouble is unless you have support and a great specialist of GP , you can go insane worrying which adds to the mix.

Then one attributes everything/ symptoms to HRT. There have been ladies who say that they had bad reactions to HRT and stopped and still had the symptoms , so realised it wasn't the HRT.

I suspect that the Premarin is very effective overall.

Again they should bring back Dydrogesterone separately for all. It has a great safety record.


I do not think they have done enough research on types of estrogens working better on a cellular level and less side effects than others.
 
We are living longer and need our bodies to work as well as they can .

More research needs to be done and the government and the medical profession should realise that preventative is far better than crisis management.

Gone are the days when women could stop work at 50 years and become a housewife quietly suffering behind closed doors. You cannot see by looking at someone if they have VA, Uti's, anxiety, night sweats etc . But they all impact on general and mental health. Our world is more fast paced and stressful than it was 50 years ago.
You are lucky if you do not have to work and can manage the symptoms without it impacting on employment. I suspect that most put up and shut up .

PMxx

[Floradora]

Great post Pepperminty. I agree totally. We are now living a good 30, 40 and even 50 years post menopausally whereas 100 years ago you would be lucky to live 10-15 years post menopause. That’s a long time to be without vital hormones in your system. And definitely I wish they would bring back dydrogesterone as a separate product. When I lived abroad I got it . It was called Duphaston or something I think. It has years of research behind it and as you say, an excellent safely record and is very well tolerated. It is structurally very similar to natural progesterone but very small doses are required to be effective so those that don’t get on with Utrogesten due to the high dosage required might very well find that dydrogesterone does the trick. It’s such a pity that it’s only available in Femoston as a combined product x

[pepperminty]

Great post Pepperminty. I agree totally. We are now living a good 30, 40 and even 50 years post menopausally whereas 100 years ago you would be lucky to live 10-15 years post menopause. That’s a long time to be without vital hormones in your system. And definitely I wish they would bring back dydrogesterone as a separate product. When I lived abroad I got it . It was called Duphaston or something I think. It has years of research behind it and as you say, an excellent safely record and is very well tolerated. It is structurally very similar to natural progesterone but very small doses are required to be effective so those that don’t get on with Utrogesten due to the high dosage required might very well find that dydrogesterone does the trick. It’s such a pity that it’s only available in Femoston as a combined product x

I wish the menopause experts would all club together - Nick Panay, Newson , and all the others and write a letter to who ever makes these decisions and reinstate it as a separate " P".

You would think such a simple thing would be possible - it isn't a new drug and may save a lot of money and NHS time in the long run. But every specialist does their own thing and even the ones that "know" each other aren't aware that it can be prescribed - if you jump through hoops.

PMxx

[Marchlove]

Please excuse my ignorance Pepperminty, but could you explain why it would be beneficial to prescribe dydrogestetone as a separate product?

Is it so that one could do a sequential regime which you can’t do with Femeston?

If so what dosage would be needed?

X

[Nas]

God it would be amazing for drydrogesterome to be available as a stand alone progesterone. I have no clue why it is only available in femeston.

We are so limited with progesterone. It’s either utrogestan, the coil or if you can get it , provera. There  are so many Oestrogen products, yet it is the progesterone which a majority of women struggle with. Pure madness!

I don’t feel we have moved that far with HRT , considering as you say PM and Flora, that women are living for many years beyond menopause now, not to mention being expected to work until we drop!

Grrhh. I hate  being a woman!

X

[pepperminty]

Please excuse my ignorance Pepperminty, but could you explain why it would be beneficial to prescribe dydrogestetone as a separate product?

Is it so that one could do a sequential regime which you can’t do with Femeston?

If so what dosage would be needed?

X

Hi,

Duphaston ( the product name) is a separate product all on its own , so you could ? can use it with any estrogen . In Femosten it is combined with the estrogen in one tablet , so you can't use it with esttogel or sandrena  etc 

It would be the same amount as in 1/10 and 2/10 which is a standard dosage . I think it is in the treatment tabs here somewhere . It would be useful to have it again , so ladies could use it with trans-dermal if Utro did not suit. It has an excellent safety record. 


PMXX

[laszla]

Coming late to this interesting thread but just wanted to say that when I read Estrogen Matters I was quite shocked that the author seemed very dismissive of body identical estrogen as here in the UK at any rate it's been drilled into us that this is by far the better formula.
I also recall that one of the equine estrogens was singled out in the book as being neuroprotective (sorry I don't have the book to hand) however a study of 2014 unequivocally concluded that "Estradiol, but not Premarin, preserves key brain regions in postmenopausal women at risk for dementia" (and it even concludes that premarin "Premarin actually appeared to accelerate some of these brain regions’ metabolic decline) https://med.stanford.edu/news/all-news/2014/03/estradiol-but-not-premarin-preserves-key-brain-regions-in-postmenopausal-women-at-risk-for-dementia-study-shows.html

I suspect that as others have suggested there is nowhere near sufficient depth and breadth of study of the different forms of estrogen and this coupled with the huge variety of individual response makes it incredibly difficult to navigate.

More so considering that, as I see it, HRT has two clearly distinct remits: one is to 'make me feel better right now', the other is 'protect me against serious future health problems that beset many women who don't supplement' (ie. cardiac, cognitivie and muscular-skeletal decline).

[pepperminty]

God it would be amazing for drydrogesterome to be available as a stand alone progesterone. I have no clue why it is only available in femeston.

We are so limited with progesterone. It’s either utrogestan, the coil or if you can get it , provera. There  are so many Oestrogen products, yet it is the progesterone which a majority of women struggle with. Pure madness!

I don’t feel we have moved that far with HRT , considering as you say PM and Flora, that women are living for many years beyond menopause now, not to mention being expected to work until we drop!

Grrhh. I hate  being a woman!

X

In 20 years time they might do something - again when a further crisis hits. I can't see the youngsters today putting up with the gas lighting and ignorance  we do.
It is a shame that Dr Currie cannot lobby the troupes and bring it back.
The louder the voice the more chance it will get done. Lets face it - it is already out there - good safety record  - suits most- could save the NHS a lot of money in time and repeat visits  etc -

PMXX

[pepperminty]

Coming late to this interesting thread but just wanted to say that when I read Estrogen Matters I was quite shocked that the author seemed very dismissive of body identical estrogen as here in the UK at any rate it's been drilled into us that this is by far the better formula.
I also recall that one of the equine estrogens was singled out in the book as being neuroprotective (sorry I don't have the book to hand) however a study of 2014 unequivocally concluded that "Estradiol, but not Premarin, preserves key brain regions in postmenopausal women at risk for dementia" (and it even concludes that premarin "Premarin actually appeared to accelerate some of these brain regions’ metabolic decline) https://med.stanford.edu/news/all-news/2014/03/estradiol-but-not-premarin-preserves-key-brain-regions-in-postmenopausal-women-at-risk-for-dementia-study-shows.html

I suspect that as others have suggested there is nowhere near sufficient depth and breadth of study of the different forms of estrogen and this coupled with the huge variety of individual response makes it incredibly difficult to navigate.

More so considering that, as I see it, HRT has two clearly distinct remits: one is to 'make me feel better right now', the other is 'protect me against serious future health problems that beset many women who don't supplement' (ie. cardiac, cognitive and muscular-skeletal decline).

 I agree - feel good now and future protect .I think the studies were done after menopause and  not well interpreted.  I think dementia went down before the hrt scare. And went up with declining use.  - and we live longer etc .
If more studies were done then we would have more idea , but this will take years and women have never been a priority.

PMXX