Hello Ann I had a few nasty side effects when I started HRT in March of this year (I'm 61). Discovered on this site, that too much oestrogen can produce the same meno symptoms as not enough . I cut my 50 patch in half and gradually built up to 3/4 and then finally applied the whole 50 patch again. HRT is now working very well for me, but I had to be patient. Also now use Vagifem and appointment with Dr soon to discuss testosterone. I tried HRT 4 years ago and after 3 weeks of bliss, had what seemed to be an allergic reaction; burning mouth, tongue, extremely painful nose. I thought it was a histermine reaction, but no one agreed with me. This time, so far, taking it slowly to begin with is working. Keep persevering (I wish I had the first time) and good luck. X