Hi Nutty and welcome to the forum, It does sound as though Kliovance is not suiting you.
I'm post menopausal by more than 5 years, I also took Kliovance and Kliofem which my GP prescribed, which I took for more than 2 years and still struggled with night sweats,
mood swings, low mood, irritability and anxiety whilst taking this. It helped the hot flushes and that was it. So I was referred at my request to a menopause clinic, where I saw a menopause specialist,
who told me the synthetic progestogen - Norethisterone in this particular oral HRT can make the horrible symptoms of low mood, irritability, sadness, and anxiety worse,
particularly if you have a past history of PMS.
So she changed my HRT to Oestrogel and Utrogestan and I can honestly say I felt a huge such improvement in my symptoms very quickly and then I was lucky enough to also have Testosterone
added in and this was the final piece I feel to my HRT jigsaw. If you can be referred to a menopause clinic then this is definitely something that I can recommend.