Side effects from progesterone/progestogens is unfortunately a main reason why many women end up abandoning HRT. Whilst Utrogesten is classed as the most ‘natural’ unfortunately it has to be taken in such a large dose that many women still suffer side effects from it. It is also sedating which can be a useful side effect in some women but cause very low mood and depression in others. The only thing I can suggest is trying an estrogen only patch, tablet or gel with Provera as the progestogen which is often fairly well tolerated as the dose required isn’t too high. It’s reasonably similar to dydrogesterone which is the progestogen used in Femoston which although you said it ‘didn’t really do anything’ sounds as though it didn’t have horrendous side effects for you either? X