Hi Fizzwizz
Sorry to hear about your hRT woes
As you blood tests have confirmed - your oestrogen levels are low and I guess, as you are taking bio-identical creams, that you are seeing a private specialist not endorsed by the British Menopause Society.
In your position as you feel unwell still, I would urge you to see a recognised specialist and get the tested and tried treatments that you need to make you feel better: try here:
https://thebms.org.uk/find-a-menopause-specialist/Also depending on how long your mirena has been in, it might need changing - strictly speaking as part of HRT 4 years is the licesned time but some docs say up to 5 years is OK.
I would attend to this first before looking at other things like testosterone. Re thyroid - a proper test should look at more than just TSH - so T3, T4 and antibodies, to test for Hashimotos, the most common form of underactive thyroid in middle-aged women (I know very little about thyroid). If you hhve the main symptoms - feeling unnaturally cold when others aren't, weight gain, and unusual fatigue - then this could mean a thyroid problem.
You don't need anti-depressants for a hormone problem!
Hope this helps and good luck
Hurdity x