Vagirux, or any other local oestrogen treatment, can be necessary alongside systemic oestrogen. The latter does not always help with symptoms of GSM and so a local treatment going straight to the source of the problem helps. I and many others here need both.
Vagifem is necessary for me along with Ovestin on the labia. I have been using Vagifem for about four years - no side effects. I'm also using 100 mcg Estradot patch.
JP x