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Author Topic: Equivalent doses  (Read 793 times)

Martasa

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Equivalent doses
« on: April 19, 2022, 07:31:14 PM »

Hi all,

I’m a new members that has been lurking around and getting lots of advice already, thank you!
Peri menopause started with an almighty bang 3 years ago. Heaviest periods, sleepless night along with all the other coming delights. Symptoms were kept relatively under control for 18 months with herbal supplements then Evorel sequi when symptoms took a turn for the worse. Only getting 2-3 hours of sleep a night are just not conducive to working with 11-16 year olds all day 😆
Anyway, Evorel patches kept peeling off and I had done a bit of research so about 6 months ago I started Sandrena 0.5 and things have started to go downhill again. Just spoken to the doctor, who until now have been very helpful. However, on querying a higher dose says she won’t do that as it increases cancer risks. I believe my dose is on the low end. Any thoughts please on how to progress with this discussion after the blood tests are in to rule out anything else?
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Martasa

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Re: Equivalent doses
« Reply #1 on: April 19, 2022, 07:46:55 PM »

Sorry, meant to say also, has anyone moved between the two and found symptoms have increased. I’m exhausted and achy to the point I feel like I’m dragging my body around from the minute I wake up. I’m wondering if there’s maybe a difference in absorption?
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Nas

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Re: Equivalent doses
« Reply #2 on: April 19, 2022, 07:57:28 PM »

You need a higher dose of oestrogen I think. Sequi is 50mg and 0.5 sandrena is about a 25 patch I think.

GPs can prescribe up to 2mg of sandrena safely. After that, you would need the guidance of a specialist.

Ask to speak to a different gp I would. The cancer risk is next to nothing. Go armed with research and get a copy of Oestrogen matters by Avum
Bluming.

Best of luck 🤞
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Martasa

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Re: Equivalent doses
« Reply #3 on: April 19, 2022, 09:50:51 PM »

Thank you!
Sandrena being a lower equivalent  dose would explain a lot.
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Louise2010

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Re: Equivalent doses
« Reply #4 on: April 20, 2022, 12:03:51 PM »

Hi Martasa - welcome!👋🏻
Agree with Nas, the risks to NOT having HRT far out weigh the risks from having it. More research has shown that some women may be more at risk from oestoporosis, dementia, cardio vascular disease with the lack of oestrogen.

The breast cancer study that saw thousands of women coming off HRT has now been shown to be flawed and there’s lots of info about that on net.

Another great book “Everything you need to know about the menopause (but we’re too afraid to ask) by Kate Muir and this podcast https://thedrlouisenewsonpodcast.podbean.com/e/136-the-lack-of-menopause-research-is-a-shocking-medical-injustice-with-kate-muir/

Maybe asking to see another gp who has more background in menopause is a good idea. Xx
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Floradora

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Re: Equivalent doses
« Reply #5 on: April 20, 2022, 12:23:03 PM »

Hi Martasa

I echo what others have said, see no reason why your dose cannot be increased if required unless you have some other particular risk factor. It’s worth having a read of the British Menopause Society/Womens Health Concern up to date guidelines which covers all aspects of current guidance together with very accurate assessment of risks and benefits. X



https://journals.sagepub.com/doi/pdf/10.1177/2053369120957514
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