Thanks for all your replies re use of vagifem. It's taken me a while to respond as took me ages to figure out where to press to reply. Also been monitoring how I feel on a daily basis now Ive cut down the daily dose. After cutting down the initial dose of vagifem I am finding I'm slipping back into how I felt before. Tired,achy, bloated and most of all the general feeling of being anxious most of the time. My g.p.wont put me on regular hrt..as I'm "post menopausal.". I wonder what t to do next..dont really want to have to use a pessary every day..Surely not every day..just dosent seem right to me..Guess I'll just see how it goes..surely pessaries are not the answer to how I feel in my head. All I know is how different I felt the first two weeks of using it..Just a bit baffled by it all.