Oestogen helped me immediately - I was very surprised at the speed, but my hot flushes stopped there and then for the first 10 days, although I do still get the odd one. My anxiety level before was awful (at one point I lost a stone in 3 weeks as I just couldn't eat), but this was massively helped by managing to sleep again, and I noticed an improvement after a week or so. However, what I'm finding now is that without my constant background anxiety I'm getting increasingly angry, which is pretty unwelcome. I've been doing CBT for about a year now and seeing a therapist once a month, and I know that has also helped, along with Mindful Self Compassion which I've been working on for the past month. I suddenly realised on Friday that I'd made multiple phone calls without even thinking about it, or spending 20 mins in the loo before hand, or having to do breathing exercises, however, I was also getting enraged over silly little things. I'm hoping that once I get used to feeling more like my old self again I'll calm down. Before HRT I said I felt 'hijacked', but now I feel strangely detatched, which is also unwelcome (although I'm blaming Covid for that one and getting out of my usual pattern of socialising).
Good luck getting the right balance for you.