I have been unable to tolerate the high doses of estrogen I need for my symptoms, and have been unable to find a progesterone yet that I can tolerate, due to previous PMDD. Even though I am post meno. I wouldn’t usually consider this but I am desperate so has anybody had any success with bio-identical hormones via a clinic such as Marion Gluck. I know they are not recommended but I literally don’t know what to do. The Newson Clinic don’t know what to do with me, and neither does my gp but my meno symptoms are intolerable.