Hi - I was on Lenzetto for nearly a year and also found the dose inconsistent. Also I found going up a whole spray at once was too much for me as I am stupidly sensitive to dose changes and had to tape off the opening to achieve half a spray which was a real faff. It did give me a good level for a while but then for some reason seemed to stop working for me so am now on Estradot patches and await my next blood test in March to see how well I am absorbing on them. Lenzetto was very easy to use but I certainly found the dose inconsistent and I seem to remember having to use a new one before it was supposed to have run out. I do think too that it is not as potent as was first thought. It certainly is a case of what suits one person may not suit another and vice versa xx