Has anyone else had problems with Utrogestan causing anxiety? I changed to Utrogestan because synthetic progesterone was causing me panic attacks. I am now using Utrogestan vaginally, every other night. But I am still having very severe anxiety on the days I am using it. Much better on the days I don’t use it. I’m told it shouldn’t cause problems this way but this absolutely not the case for me, it would appear. I feel stuck now.