Hi ABC123,
I’m sorry I’m a bit late to reading your post but I was in a similar position to you last year as my estradiol levels were 81 after being on HRT for 2 years. I was on a 75 mg patch and utrogestan. I then tried Estrogel but after a week had to give that up as I felt awful and go back to a patch.
GP admitted they didn’t know what to do, so I saw a private menopause specialist. She said she thought I was a poor absorber. I take medication too which is known to affect HRT, so I was at a complete loss. She suggested I tried Lenzetto, (3 sprays) which I did, she said this had worked well for others in a similar position. I also got a mirena coil fitted locally at a private hospital as I was also having intermittent bleeding, which utrogestan wasn’t solving.
I have to say, Lenzetto has been a lifesaver and I took to it straight away. I have since had a blood test (taken just before I sprayed Lenzetto that day) and my levels were 452. I’d been on Lenzetto for 3 months at that point. I know Lenzetto doesn’t work for everyone, but fortunately it did for me. I knew things had improved though within a week, as I was sleeping better and my anxiety improved so much. I feel so much better now, nearly a year on.
I’m not suggesting that being a poor absorber is your problem, but it could be a possibility, that might be worth considering and a different form of HRT, which you are doing with Sandrena, that might be the answer. If not, it might be worth trying Lenzetto?
I too have osteoporosis in my family -both my parents had it, so I’m keen to make this work for me too.
Good luck and I hope things improve for you.