Hi All I'm a new to the forum , but have been a regular reader and find the information and sharing of personal experience really interesting. So I'm hoping some of you would be able to shed some light on my recent experiences and share your wisdom with me. Here is a condensed version of my history : I had an emergency hysterectomy and BSO at 21; due to the extent of the ENDo I was not allowed oestrogen straight away; from around 23 I was prescribed Oestrogen and have been pretty stable up until the last 2 /3 years, I am now 51. I was on Climival 1mg twice a day but when this was withdrawn I tried patches estroderm 100mcg. Shortly after starting I started having accelerated hair loss/ thinning ; night sweats, waking with palpitations and subsequent insomnia. I do a great deal of high energy cardiovascular exercise and through researching found out that I was probably oestrogen dumping- when your exercising intensively accelerated transfer of oestrogen from the patchwhich then rendered the patch 'empty' for the subsequent days until changed and it would all happen again; So I put it down to this - big peaks and trough etc. I changed to oestrogel. This improved minimally in the short term, during lock down I would say my exercise has increased. Recently I have had an increase in issues with sudden waking/palpitations/feeling I cannot breath and then remaining awake for hours - feeling wired but not anxious . I have no worries or anxieties, not churning things over etc. I just cannot sleep. I believe this is cortisol spikes. I have tried using the gel both morning and night - divided doses etc. and increasing the dose to 4 pumps a day. I am also on a small dose of tesogel which I apply in the morning. I have never been prescribed progesterone by I am wondering if the increased symptoms I am now getting could be due to progesterone deficient sleep apnoea? IF so would urogestan 100mg be a valid and safe option to try - any one on it post hysterectomy - I've read various good and bad reports . Or should just keep upping the dose of my oestrogen/trying new spray lenzetto (GP happily prescribed ) ? Any thought? Thanks Cath