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[Dada39]

Hello,
I am wondering if i am not histamine intolerant.
Everytime I try hrt, my hair star shedding on the only Oestradiol part : femoston then Oestrogel.

Before chirurgical menaupose I never has issue When  taking hrt  for fertiliy traitment.

I am feeling depressed and hopeless. I am 39 I need the oestrogens but I don't want to lose my hair. I am early menauposal and infertile, that's alrezdy too much. If I knew that my life would be this misérable I would have keep my ovary full of endometrioma.

I am missing my life, I really down, anxiety, Oestrogel that I tried for one cycle last month gave me bad anxiety and utrogestan insomnia.
I have a lot of symptome. I'm too young for this. I l scared that my partner leave me because of what i became, like i don't have joy. I think i am  doing a dépression but scare to take As.
Sorry English is not my lother tongue.

[CLKD]

Morning.  Where do you live?

Do U talk with your partner, this is the 1st route.  Who over-sees your replacement regime?  There are several threads here recently about hair shedding, do read. 

[Dada39]

Hi Ckld,
Thanks for the response. I a m based in France. I am honna see another spécialiste.
But ly feat is I will loose my hair if I use a HRT.
I used a lot of Oestradiol tablet to try to conceive and never had an issue. Everytime I used 2mg vaginally to prepare an embryo transfert. Never lost hair...
I cannot cope with that, it gived more anxiety and stress. Should I stop hrt and try to live mi life with menospymptom and bone and health risks?

[CLKD]

Nope.  Read the various threads here about hair loss.  Keep a mood/food/symptom diary to take 2 the appt.. 

There are many options for replacement threrapy but it can be Trial and Error! How is your diet overall?

[Ana21]

Hello Dada39!

I'm so sorry to hear you're feeling anxious and depressed.

Estrogen can seem like a double-edged sword when it comes to hair.  Too much or too little can trigger hair loss.

Hormonal hair loss is complicated.  I'm also experiencing hair loss.  In my case, it's likely due to low estrogen (not absorbing the patch, confirmed by blood test) and a history of androgen sensitivity.  My doctor has switched me to an oral estrogen to raise my estrogen level.  Looking at the side effects of my new medication, it lists both loss of scalp hair and increased hair growth.

During perimenopause, some women experience hair loss due to estrogen dominance.

During menopause, some women experience hair loss due to low estrogen.

I'm oversimplifying it, of course.  Hair loss due to hormonal imbalance is complex and requires correct diagnosis and treatment by an expert.  I've been referred to a dermatologist for that reason, and I've seen an endocrinologist in the past.

Estrogen can trigger changes to the hair growth phases:  anagen (growing phase), catagen (transition phase), telogen (resting phase), and exogen (shedding phase).  Here's an article that describes how estrogen can cause hair to enter the transition phase prematurely and stay in the resting phase for a longer period, resulting in hair loss.  The good news is that this type of hair loss isn't permanent.

Estrogen Leads to Reversible Hair Cycle Retardation through Inducing Premature Catagen and Maintaining Telogen.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390338/

And here is an article that describes (with pictures!) the phases of hair growth and hormonal regulation of hair follicles.

Hormonal Effects on Hair Follicles
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432488/

Have you spoken to your doctor about your hair loss and your observation that it's connected to your estrogen therapy?  Your doctor will want to rule out other causes, such as low thyroid, etc.  If you haven't done so already, ask for a referral to a specialist who can diagnose the cause of your hair loss, typically a dermatologist.  If the dermatologist thinks it's due to hormonal imbalance, you may be referred to an endocrinologist or other specialist for further investigation and treatment.

Try not to despair.  I'm sure it will all get sorted out.

[Dada39]

Hi Ana21,
Thank you for your response. It's interesting.
I'm sorry that you are struggling with hairloss too.
All my blood testing were good. I had ovariectomy so chirurgical menaupose. I never had issue before and after the surgery. It 's only as soon as I Start taking oestrogen. When I stopped taking the oral tablet 2mg  the shedding stopped 6 weeks after. I could felt a my hair tingling and détached from my scalp and then fall. After stopping taking hrt. It was awfull feeling.
I stopped the oestrogel for now.

[Ana21]

Dada39,

I'm concerned that you've stopped the oestrogel.  You're too young to stop hormone replacement therapy.  The health consequences are significant.  I hope some of the women with POI/surgical POI will share their knowledge and experience.

I understand the hair loss is alarming and you don't want to lose any more, but it's not worth sacrificing your health now and in the future.  You have many years ahead and these dark days will pass.

Please see a specialist to diagnose the type of hair loss you're experiencing, in order to determine the appropriate treatment.  There are many causes of hair loss, including autoimmune disorders.  Stress and illness can trigger a shed and temporary hair loss.  You need a diagnosis in order to find the best path forward.

I hope you have lots of support in your life to help you get you through this difficult time.

Keep us posted.  Let us know what the doctor says.