I was diagnosed about 10 years ago, and for most of that time all I've needed was the odd period of using Dermovate on a weekly basis and it's calmed down. I had breast cancer treatment 5 years ago, and the oral steroids they give you during chemo had the effect of completely stopping the LS in its tracks for several years. However, I'm now having a huge flare-up - I think caused by a combination of being in a sexual relationship again after years of celibacy, also the meds I'm on for depression and anxiety make me chronically constipated which really doesn't help. My LS has always been worst in the perineal area, which I think is connected with the fact that I tore there during both of my two labours; I had a look a couple of days ago and the whiteness has increased dramatically, also there's what looks like a small ulcer which is extremely painful. I'm seeing my GP tomorrow and wondering what she'll suggest, not looking forward to having to have another biopsy if that's required.....