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Author Topic: Progesterone intolerance  (Read 1313 times)

lindseywalsh

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Progesterone intolerance
« on: January 26, 2021, 07:05:33 PM »

Hi,

I know that this is a very common theme. I have seen mentioned on here that some women take a super low dose of utrogestan every 5-6 weeks and are routinely monitored via ultrasound to check the endometrium.

Is anyone using this regime? And if so how much is your very low dose?

I am under the John Studd clinic. They are recommending 10 days 100mg vaginal utrogestan per month, or 7 days if that’s all I can tolerate (with an annual ultrasound). I haven’t tried this regime yet - consultant has advised me to go back to 4 pumps of oestrogen for a month or so to “let things settle” (I had been avoiding using utrogestan for the 18 months of HRT, so only sporadically, but the oestrogel has been life changing). I am nervous about this as it has taken me a month to recover from the last time
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sheila99

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Re: Progesterone intolerance
« Reply #1 on: January 26, 2021, 10:36:38 PM »

That sounds like good advice. I just get fatigue so can tolerate to 200mg x 12 days but I use a long cycle. This works better if you're late peri or meno so your own hormones don't cause bleeds at odd times. Have you tried other forms of progesterone?
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Perinowpost

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Re: Progesterone intolerance
« Reply #2 on: January 27, 2021, 07:33:47 AM »

Hi Lyndseywalsh

Welcome to the forum. I use that regime i.e., 7 days utrogestan vaginally a month with evorel 50 patches. I found out about Studd’s regime on this forum (although I’ve never paid to see him) and it works for me. I am extremely intolerant to progesterone having tried everything (and I mean everything currently available) and this is the only regime I can tolerate.

I have annual scans and everything is fine. I wouldn’t do it without supervision though as you will need monitoring. Wishing you well xx
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lindseywalsh

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Re: Progesterone intolerance
« Reply #3 on: January 27, 2021, 09:30:49 AM »

Thanks Sheila99.

What is your long cycle?
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sheila99

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Re: Progesterone intolerance
« Reply #4 on: January 27, 2021, 10:20:33 AM »

6 weeks.
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Mary G

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Re: Progesterone intolerance
« Reply #5 on: January 27, 2021, 12:26:38 PM »

I am a former patient of Professor Studd and his regime worked well for me for a number of years.   He introduced me to Oestrogel which finally got rid of my sweats.

As I got older (I'm now 59) I found the bleeds made me feel terrible and I finally got to the stage where I could only take a few vaginal 100mg Utrogestan capsules each cycle which I stretched to about five or six weeks. Utrogestan also destabilised my hormones and caused migraines.

I have a gynecologist and I have regular scans and I always had excellent clearance even after using just a few 100mg capsules but obviously there is no guarantee everyone is the same.

I would try it and just have regular scans, you have nothing to lose!
   
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lindseywalsh

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Re: Progesterone intolerance
« Reply #6 on: January 27, 2021, 07:43:53 PM »

Thanks Mary G.

Couple of questions ....

1. Did you take the utrogestan vaginally?
2. How many did you use each cycle approx?
3. Did you use the utrogestan on consecutive days? Or alternate days?
4. How much oestrogel do you use now?

Interesting that as you got older your reaction to utrogestan has worsened - I feel this has happened to me.

I understand that everyone,s reaction is different, and I won,t take undue risks.

Thankyou for your feedback
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Sophie20

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Re: Progesterone intolerance
« Reply #7 on: April 10, 2021, 11:38:09 AM »

Dear Mary G
I have been following your posts with interest as I am progesterone intolerant and have come to a place where I don't know what to do next.  I have tried utrogestan, and Cyclogest, and sadly can't cope with the migraines, overly lax muscles and low libido etc.  I have tried lowering the doses, but I still have issues.  I would love to find a progesterone that would suit me, and a specialist who can point me in the right direction before I throw in the goose!  I have thought about contacting Mr Studd, but wonder if I would cope with 7-10 days of Utrogestan.  Unfortunately progestins were poorly tolerated too.  56 going on 80!  Looking for answers!
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Mary G

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Re: Progesterone intolerance
« Reply #8 on: April 10, 2021, 08:09:42 PM »

Sorry, one only just had this brought to my attention, I haven't logged on for a while!

lindsay, I can't remember if I sent you a PM but just in case I forgot :

1.  Yes, I used Utrogestan vaginally.

2.  I mostly used between 3 and 7 x 100mg capsules per cycle depending on migraines.  On one occasion it was so bad I only used 1 capsule.

3.  I used it on consecutive days.

4.  I was using three pumps of Oestrogel initially but then reduced to one pump of Oestrogel with testosterone and 50mg progesterone every day.  I switched to 1 spray of Lenzetto a month ago.

Sophie20, I will bump up my thread in the Alternative Therapies section and send you a PM.

Professor Studd has retired but his colleagues have taken over the clinic and they are also very good.   You could try taking 100mg Utrogestan vaginally for 7 days each cycle and have regular transvaginal scans.   That regime worked well for me for a number of years until I hit the buffers with Utrogestan. 

Once I was very post menopause, things changed and I could no longer tolerate 100mg Utrogestan or the ups and downs of a cycle because they triggered my silent migraines and the bleeds made me feel ill.   I now need a stable, lowish dose of oestrogen and progesterone every day with a small bead of testosterone.


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