If you have a look at Dr. Sarah Myhill's website, she has a lot of factual information on Pregnenolone. She has switched from DHEA prescribing to it for its greater physiological support. She did prescribe it for me at one time and I seem to recall it not agreeing with me, but regret possibly not sticking with it for longer as I don't think I gave it long enough to prove itself. Nothing to do with menopause support at the time, but a maladaptive stress response which, in hindsight, may have been menopause-related!!!!! Chicken and egg! Have you a particular reason for your interest in it?