Hi Wendy, I had to stop using them after 2 weeks, as they left angry red marks on my hips which have taken about 5 weeks to fade away. I am guessing there is something in the adhesive that we are sensitive to? I was so hopeful for being completely transdermal too.
I am back on Estradot 50 patches which don't irritate my skin and stay stuck on very well. I am also on Utrogestan 100mg daily, but am having an awful lot of stomach problems and a sharp pain in my right breast after trying Tostran gel too, (as recommended by my meno clinic gynae Dr). I think I may not be suited to HRT, as have been trying to find the right regime for over a year now at age 64, but it is the only thing that gets rid of my hot flushes!
Stuck between a rock and a hard place!
I hope you find the best thing for you. x